- #11 (CB VERNON HARGREAVES) - Hargreaves has been solid but has only 1 career interception and has missed 22 games the last two seasons due to injury.
- #41 (LB REGGIE RAGLAND) - Injuries have derailed Ragland's career, and he's currently being juggled around the ass-end of the Chiefs depth chart.
- #106 (CB ERIC MURRAY) - Murray is a journeyman nothing who may be in his final NFL stop in Cleveland.
- #117 (WR PHAROH COOPER) - Has emerged as a kick return specialist, but is little-utilized in the receiving game. Missed nearly all of 2018 with an ankle injury.
- #206 (WR MIKE THOMAS) - Career highlights so far have been a 4 game PED suspension and a lost 2018 season to a groin injury.
- #9 (LB LEONARD FLOYD) - Floyd has missed 10 games in his three years, but started all 16 games in 2018. He has 1 pick, 1 forced fumble, 3 fumble recoveries, 32 QB hits, 114 tackles, 1 safety, and 15.5 sacks. Made the PFWA all-rookie team in 2016.
- #56 (OL CODY WHITEHAIR) - Has started every game in his Bears career, and showed the ability to excel at LG, RG, and C. Has issues with snaps, but was a Pro Bowler in 2018 regardless.
- #116 (LB NICK KWIATKOSKI) - Kwiatkoski has been a serviceable backup, and while he struggles in coverage, he has shown a propensity against the run and is a stalwart special teams presence. Injuries are a concern.
- #124 (S DEON BUSH) - His first few years in the NFL have been almost exclusively in use in special teams, with occasional emergency starts. In 2018 he got more opportunity, finishing the season with a forced fumble and a sack. Has had a tremendous 2019 camp/preseason, and may be in line for an emergent season (on a contract year).
- #3 (DL SOLOMON THOMAS) - His career thus far has sputtered, and Thomas has endured a lot of personal turmoil off the field that has no doubt impacted his focus and trajectory. There is still great potential there, and the 49ers are optimistic about his future, but 2019 is his crucial year to make great strides.
- #36 (S BUDDA BAKER) - After cutting his teeth in a humble rookie year, Baker seems to be settling in as a reliable, versatile tool for the Cardinals. He has yet to record an interception, but is able to play virtually any defensive back position with skill. The team has their sights set on making him their starting Free Safety in 2019.
- #67 (RB ALVIN KAMARA) - Kamara emerged as the best running back from the 2017 class, earning ROTY honors and 2 Pro Bowl selections. Currently one of the elite backs in the NFL.
- #111 (S TEDRIC THOMPSON) - With Earl Thomas moving on, the Seahawks have high hopes for Thompson. With a lot of looks in 2018, he's in a position to become starter.
- #117 (WR JOSH REYNOLDS) - Reynolds has emerged as a favorite target of Jared Goff, and is building a nice career resume for himself out in Los Angeles.
- #197 (CB JEREMY CLARK) - Has had little impact thus far. On IR for the 2019 season.
- #221 (S SHALOM LUANI) - Finding a foothold as a special teamer, but still battling for a roster spot.
- #2 (QB MITCHELL TRUBISKY) - We all know about Mitch's ups and downs, but there is a ton of optimism about year 2 in Nagy's offense. Trubisky needs to have a defiant, stalwart year to prove that he is past simple "great potential" and graduated into "NFL mainstay."
- #45 (TE ADAM SHAHEEN) - Jury is still out on Shaheen, whose injury concerns and lack of standout play have fans worried. The current 2019 season is likely his last chance to prove Pace didn't make a mistake taking him so highly in the draft.
- #112 (S EDDIE JACKSON) - Jackson is arguably the best safety in the NFL, emerging as a game-changing presence and made the Pro Bowl in 2018 in recognition of his terrific year.
- #114 (LB JOEL IYIEGBUNIWE) - Iggy is something of a unique case, as he was drafted almost exclusively to bolster special teams. In his first seasons in the NFL, his stats are rather meaningless, but many will be watching in 2019 to see if he can take advantage of more opportunities to distinguish himself as a vital cog in a championship window.
- #119 (RB TARIK COHEN) - The Human Joystick since Day 1 showed that he is a dynamic, dangerous presence anytime he's on the field. Versatile in running, passing, and return dimensions of football, Cohen's fresh off a Pro Bowl nod and should continue to dazzle in 2019.
- #70 (LB FRED WARNER) - Warner is emerging as a leader for the 49ers, calling plays from the defensive huddle, and if the game slows down for him in 2019, he could become known outside of San Fran. Had minor knee surgery this offseason, but appears to be doing well in camp.
- #105 (WR ANTONIO CALLAWAY) - Despite showing enormous promise, Callaway is quickly burning his bridge to the NFL. After a run in with police last August due to driving with a suspended license, drugs, and guns, he followed that up this year with a 4-game suspension for violation of the league's substance abuse policy.
- #51 (WR ANTHONY MILLER) - Miller came to the Bears with a lot of swagger, and backed it up. Despite being hobbled with shoulder injuries, Miller snared 7 touchdown catches his rookie season. If he stays healthy, he'll be another big weapon for a dangerous Bears receiver corps.
- #87 (RB DAMIEN HARRIS) - Struggling with injuries sustained in a preseason game.
- #162 (LB CAMERON SMITH) - Projected to be a special teams presence for Minnesota his rookie season.
- 4th round in 2020
- #73 (DAVID MONTGOMERY) - While it's obviously still extremely early, Montgomery's camp and preseason has been very exciting, demonstrating why Pace was so engrossed in moving up to acquire him in the 2019 draft.