Politics-Free Pandemic/COVID-19 Discussion

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mmmc_35
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Re: Pandemic (non political) Thanks

Sun May 31, 2020 9:53 am

So I get these tests are supposed to be 70% accurate. But who knows. I assume its known here I'm not to dumb. While I spell and write like a moron, that is generally not who I am. I cant explain everything about this but know it's really wierd.. The effectiveness is not their reason. I cant get much into some of that but its wierd.

Side note. Last night we dealt with riots. It was crazy. I'm fucking wierd, but for some reason chaos and I are bed fellows. Its really unique though watching things talked about on tv happen. Then watching tv and realize how wrong they are. I've known this for a while but a news crew right behind me literally told the story about 125° from the truth.

My employer blew the budget on the Rona... so we will see how they handle tonight.
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IE
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Re: Pandemic (non political) Thanks

Sun May 31, 2020 1:12 pm

Nobody said you weren't smart, dude. I actually assume people are until they prove otherwise.

I can relate to the tendency to read a lot into things, and over-analyze. So I try to use Occam's Razor to keep focused. Remember literally nobody can keep secrets. So anything you're concerned about that requires many people keeping their mouth shut... it basically doesn't happen. Especially if the number gets higher than just a handful.

I had a girlfriend in college that lived by the philosophy that you should assume everyone you meet is insane until they prove otherwise... but that was just too cynical for me. I mean, it does prove to be true sometimes - but I just can't operate like that. I shouldn't have broken up with her that 3rd time. She's a billionaire now. lol
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mmmc_35
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Re: Pandemic (non political) Thanks

Sun May 31, 2020 7:47 pm

I operate like your college girlfriend.
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thunderspirit
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Re: Pandemic (non political) Thanks

Fri Jun 05, 2020 11:51 pm

I'm no expert in any fashion, I just read a fair bit about COVID. To me the concerning thing is less the (roughly) 1 in 10 who are symptomatic that have to be hospitalized -- though that's certainly sobering -- and more the long-term damage that seems to afflict a good chunk of those who contract and recover without hospitalization.

My wife called it our generation's polio, and she has a point (despite some obvious dissimilarities).
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IE
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Re: Pandemic (non political) Thanks

Tue Jun 23, 2020 10:28 am

It is false that the uptick in cases is related to a dramatic increase in testing. Testing did increase a while back - but since mid May has stayed at a relatively stable 450-500K/day average.
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dplank
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Re: Pandemic (non political) Thanks

Wed Jun 24, 2020 11:06 am

Hospitalizations are exploding here in south florida....fucking morons just couldn't deal with the lockdown and pushed it too fast. The hospital closest to my home is reaching capacity (and the Covid sectored off section is over capacity and leaking over into the non-covid areas of the hospital, increasing risk of cross contamination).

All the jokes you hear about Florida are true. it's a shit show down here. You are equally likely to get fucked with if you are wearing a mask (by aholes on one side) or not wearing a mask (by aholes on the other side). Why can't everyone just do what's right and stop bickering about every goddamn thing all the time. 120K people are dead and all we can do is argue and point fingers at one another. Health isn't political and I'm glad this thread isn't political, thx again to the mods for keeping this place politics free!

So I'll use this small platform to shout out to the nurses and others working in those hospitals. They are taking their lives in their hands to help others, I can't think of anything more noble than that. I overheard two nurses talking while I was waiting to pick up my wife yesterday from the hospital and it was heart breaking - they were basically counting the days until they were rotated back into the "covid ward", figuring out how to distance from their families during that stretch, and scared to death about catching it. God bless them.
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IE
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Re: Pandemic (non political) Thanks

Wed Jun 24, 2020 4:29 pm

Article from some SF web site. I wouldn't normally share something like this because who knows how credible or well-researched the site is. But I will share it because the theme is consistent with what I've heard from my wife's experience at Sinai Grace in the D. And also from a friend of mine who is a cardiovascular surgeon and tenured professor at U of Michigan Med School/Hospital. What he's related publicly is Covid acts more like a cardiovascular disease than respiratory. Even though the transmission and symptoms are respiratory in nature. It causes serious permanent damage and does cause heart attacks and strokes even with some younger people. This is not something that "young healthy sports stars shouldn't worry about". This is something everyone should care about.

https://www.sfgate.com/news/editorspick ... 347792.php
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mmmc_35
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Re: Pandemic (non political) Thanks

Fri Jul 03, 2020 5:55 am

So my work did the antibody tests. Those who already had a positive viral test didnt participate and those on their days off did not participate. The tests are supposed to be 70% accurate.

We had 20% of the approximately 350 tests come back positive. I included the viral positives in the group also. We had 1 hospitalization, a guy with major lung issues previously.

I find this suprising. I figured it would be closer to 50%. A work group whom has not stayed home and has a ton of contact with large swaths of the populace. While cleaning and PPE have obviously helped, but I still find 20% strange.

My conclusion is it may not be as transmittable as suggested. I have personally dealt with a couple of active positive viral people. 2 OD's and 2 work people, that I know of. I do not have the antibodies even though I had no PPE on any contact. I got in trouble for not putting on PPE before CCR on the 2 ODs. 1 lived 1 did not. Seemed wrong to stop go out to my car and get gear while someone's dead.

Just some info for you all.
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dplank
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Re: Pandemic (non political) Thanks

Fri Jul 03, 2020 11:01 am

mmmc_35 wrote:
Fri Jul 03, 2020 5:55 am
So my work did the antibody tests. Those who already had a positive viral test didnt participate and those on their days off did not participate. The tests are supposed to be 70% accurate.

We had 20% of the approximately 350 tests come back positive. I included the viral positives in the group also. We had 1 hospitalization, a guy with major lung issues previously.

I find this suprising. I figured it would be closer to 50%. A work group whom has not stayed home and has a ton of contact with large swaths of the populace. While cleaning and PPE have obviously helped, but I still find 20% strange.

My conclusion is it may not be as transmittable as suggested. I have personally dealt with a couple of active positive viral people. 2 OD's and 2 work people, that I know of. I do not have the antibodies even though I had no PPE on any contact. I got in trouble for not putting on PPE before CCR on the 2 ODs. 1 lived 1 did not. Seemed wrong to stop go out to my car and get gear while someone's dead.

Just some info for you all.
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mmmc_35
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Re: Pandemic (non political) Thanks

Fri Jul 03, 2020 10:52 pm

Thanks, yeah a deputy for a moderate sized department. Most our staff works the jail, court, conveyance. Right around 20% work patrol like I do now. The jail generally houses 1000 inmates. We had something like 30 positive viral inmate tests. Social distance, masks, etc are kind of out the window. While Deputies have masks Inmate's don't. Most Deputies dont wear them because you live with these people 8-12 hrs a day. The jail the general contact with numerous people is off the charts.

The numbers just dont show what I thought they would. Not positive or negative.
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mmmc_35
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Re: Pandemic (non political) Thanks

Tue Jul 07, 2020 5:31 am

The administration just reposted the numbers and its actually 33% of the department that has the antibodies.
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IE
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Re: Pandemic (non political) Thanks

Tue Jul 14, 2020 9:16 am

Hey - curious if there has been any special policy established for the antibody-positive folks. Are they operating as if that means not at risk or risk to others? Or still same policy around PPE and such?
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mmmc_35
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Re: Pandemic (non political) Thanks

Tue Jul 14, 2020 9:52 am

IE wrote:
Tue Jul 14, 2020 9:16 am
Hey - curious if there has been any special policy established for the antibody-positive folks. Are they operating as if that means not at risk or risk to others? Or still same policy around PPE and such?
No there isn't. One would think admin would but there hasn't been. If admin was truely worried positive folks would work in covid areas or calls.

The county just put a mask order in effect and it applies to everyone. Honestly I am not directly obeying. I ask people if they want me to have it on. But facial expressions are so much of language. Convincing a suicidal chick you care, (weather you do or dont) is hard without human interaction. Or 94 year old deloris that a man didn't break into her house she was dreaming.
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IE
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Re: Pandemic (non political) Thanks

Wed Jul 15, 2020 12:10 pm

mmmc_35 wrote:
Tue Jul 14, 2020 9:52 am
IE wrote:
Tue Jul 14, 2020 9:16 am
Hey - curious if there has been any special policy established for the antibody-positive folks. Are they operating as if that means not at risk or risk to others? Or still same policy around PPE and such?
No there isn't. One would think admin would but there hasn't been. If admin was truely worried positive folks would work in covid areas or calls.

The county just put a mask order in effect and it applies to everyone. Honestly I am not directly obeying. I ask people if they want me to have it on. But facial expressions are so much of language. Convincing a suicidal chick you care, (weather you do or dont) is hard without human interaction. Or 94 year old deloris that a man didn't break into her house she was dreaming.
Yeah - I get that. Try a clear face shield... my wife sometimes uses those in treating folks (she's a rehab speech therapist). Her hospital in the D is mostly Covid free right now (which is amazing). But a positive case pops up now & again among the regular patients (one did yesterday), so they keep their guard up very carefully.

Interesting comment about the 94 year old. At my wife's work an 86 year old man with dementia had to get an enema one day, and then afterwards insisted he had been anally raped by a male nurse while other nurses held him down. 4 cops had to visit multiple times to "investigate" the claim... it was ridiculous. I'm not a "defund" guy - but I AM in favor of looking at the roles cops have to play and narrowing them. When social safety nets are taken away, it all falls on the cops to fix. That sucks.
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Re: Politics-Free Pandemic/COVID-19 Discussion

Wed Jul 15, 2020 2:36 pm

Our office is going back to working in office every other day (half time). There has been a spike in out county and our director has had friends who have gotten the 'rona.

Kind of sucks. We just got back to full time in the office in June. Now we will be half time thru September.

Probation is not a job you can do over the phone. Just went out for a home visit today (said fuck it, have to make sure this person is actually a person) and was told by the occupants at that address that they don't know the people I was looking for. They further reported they had been in this home for over 2 months!!!! This was a case transferred from another county. (Knew it wasn't the kid's mom as we have pics of her and Facebook helps).
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Re: Politics-Free Pandemic/COVID-19 Discussion

Wed Sep 09, 2020 7:11 am

https://elemental.medium.com/a-supercom ... cb8eba9d63
According to the team’s findings, a Covid-19 infection generally begins when the virus enters the body through ACE2 receptors in the nose, (The receptors, which the virus is known to target, are abundant there.) The virus then proceeds through the body, entering cells in other places where ACE2 is also present: the intestines, kidneys, and heart. This likely accounts for at least some of the disease’s cardiac and GI symptoms.
But once Covid-19 has established itself in the body, things start to get really interesting. According to Jacobson’s group, the data Summit analyzed shows that Covid-19 isn’t content to simply infect cells that already express lots of ACE2 receptors. Instead, it actively hijacks the body’s own systems, tricking it into upregulating ACE2 receptors in places where they’re usually expressed at low or medium levels, including the lungs.
In this sense, Covid-19 is like a burglar who slips in your unlocked second-floor window and starts to ransack your house. Once inside, though, they don’t just take your stuff — they also throw open all your doors and windows so their accomplices can rush in and help pillage more efficiently.
The renin–angiotensin system (RAS) controls many aspects of the circulatory system, including the body’s levels of a chemical called bradykinin, which normally helps to regulate blood pressure. According to the team’s analysis, when the virus tweaks the RAS, it causes the body’s mechanisms for regulating bradykinin to go haywire. Bradykinin receptors are resensitized, and the body also stops effectively breaking down bradykinin. (ACE normally degrades bradykinin, but when the virus downregulates it, it can’t do this as effectively.)
The end result, the researchers say, is to release a bradykinin storm
By acting like a natural ACE inhibitor, Covid-19 may be causing the same effects that hypertensive patients sometimes get when they take blood pressure–lowering drugs. ACE inhibitors are known to cause a dry cough and fatigue, two textbook symptoms of Covid-19. And they can potentially increase blood potassium levels, which has also been observed in Covid-19 patients. The similarities between ACE inhibitor side effects and Covid-19 symptoms strengthen the bradykinin hypothesis, the researchers say.
ACE inhibitors are also known to cause a loss of taste and smell. Jacobson stresses, though, that this symptom is more likely due to the virus “affecting the cells surrounding olfactory nerve cells” than the direct effects of bradykinin.
As Jacobson and team point out, several drugs target aspects of the RAS and are already FDA approved to treat other conditions. They could arguably be applied to treating Covid-19 as well. Several, like danazol, stanozolol, and ecallantide, reduce bradykinin production and could potentially stop a deadly bradykinin storm. Others, like icatibant, reduce bradykinin signaling and could blunt its effects once it’s already in the body.
Interestingly, Jacobson’s team also suggests vitamin D as a potentially useful Covid-19 drug. The vitamin is involved in the RAS system and could prove helpful by reducing levels of another compound, known as REN. Again, this could stop potentially deadly bradykinin storms from forming. The researchers note that vitamin D has already been shown to help those with Covid-19.


If nothing else, stock up and start taking some vitamin D supplements (not a fricken multivitamin), and it will help lessen any symptoms if you do catch the virus.
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